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ZOLOFT® (sertraline HCl) Overdosage

10 OVERDOSAGE

Human Experience

The most common signs and symptoms associated with non-fatal ZOLOFT overdosage were somnolence, vomiting, tachycardia, nausea, dizziness, agitation and tremor. No cases of fatal overdosage with only sertraline have been reported.

Other important adverse events reported with ZOLOFT overdose (single or multiple drugs) include bradycardia, bundle branch block, coma, convulsions, delirium, hallucinations, hypertension, hypotension, manic reaction, pancreatitis, QTc-interval prolongation, Torsade de Pointes, serotonin syndrome, stupor, and syncope [See Clinical Pharmacology (12.2)].

Overdose Management

No specific antidotes for ZOLOFT are known. Contact Poison Control (1-800-222-1222) for latest recommendations.

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